Journal: Pharmacognosy Magazine

Article Title: Simultaneous determination of 11 bioactive compounds in Jaeumganghwa-tang by high performance liquid chromatography-diode array detection

doi: 10.4103/0973-1296.133267

Figure Lengend Snippet: The chemical structures of 11 marker compounds of Jaeumganghwa-tang. (1) 5-Hydroxymethylfurfural, (2) mangiferin, (3) paeoniflorin, (4) nodakenin, (5) naringin, (6) hesperidin, (7) decursinol, (8) berberine, (9) glycyrrhizin, (10) atractylenolide III and (11) decursin

Article Snippet: Decursinol was purchased from Elcomscience Co., Ltd. Paeoniflorin was purchased from Wako Co., Ltd. 5-HMF was purchased from Sigma Aldrich Co., Ltd. Mangiferin was purchased from Fluka Co., Ltd. Atractylenolide III was purchased from Chromadex Co., Ltd.

Techniques: Marker

Journal: Pharmacognosy Magazine

Article Title: Simultaneous determination of 11 bioactive compounds in Jaeumganghwa-tang by high performance liquid chromatography-diode array detection

doi: 10.4103/0973-1296.133267

Figure Lengend Snippet: (a) Chromatograms of Jaeumganghwa-tang standard mixture and (b) sample. (1) 5-Hydroxymethylfurfural, (2) mangiferin, (3) paeoniflorin, (4) nodakenin, (5) naringin, (6) hesperidin, (7) decursinol, (8) berberine, (9) glycyrrhizin, (10) atractylenolide III and (11) decursin

Article Snippet: Decursinol was purchased from Elcomscience Co., Ltd. Paeoniflorin was purchased from Wako Co., Ltd. 5-HMF was purchased from Sigma Aldrich Co., Ltd. Mangiferin was purchased from Fluka Co., Ltd. Atractylenolide III was purchased from Chromadex Co., Ltd.

Techniques:

Journal: Pharmacognosy Magazine

Article Title: Simultaneous determination of 11 bioactive compounds in Jaeumganghwa-tang by high performance liquid chromatography-diode array detection

doi: 10.4103/0973-1296.133267

Figure Lengend Snippet: Liquid chromatography-mass spectrometry spectra of maker compound in Jaeumganghwa-tang. (1) 5-Hydroxymethylfurfural, (2) mangiferin, (3) paeoniflorin, (4) nodakenin, (5) naringin, (6) hesperidin, (7) decursinol, (8) berberine, (9) glycyrrhizin, (10) atractylenolide III and (11) decursin

Article Snippet: Decursinol was purchased from Elcomscience Co., Ltd. Paeoniflorin was purchased from Wako Co., Ltd. 5-HMF was purchased from Sigma Aldrich Co., Ltd. Mangiferin was purchased from Fluka Co., Ltd. Atractylenolide III was purchased from Chromadex Co., Ltd.

Techniques: Liquid Chromatography, Mass Spectrometry

Journal: Molecules

Article Title: Pharmacological Effects of “Jutsu” ( Atractylodis rhizome and Atractylodis lanceae rhizome ) on 1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-Induced Head Twitch Response in Mice (I)

doi: 10.3390/molecules190914979

Figure Lengend Snippet: Chemical structures of atractylenolide III and β-eudesmol.

Article Snippet: Atractylenolide III (Lot No. WEN2356) and β-eudesmol (Lot No.WEG2032) were purchased from Wako Pure Chemical Industries Ltd. (Tokyo, Japan) and were dissolved in corn oil (Lot No.2012H2137, Junsei Chemical Co., Ltd., Tokyo, Japan), while control animals were orally administered with corn oil at a volume of 3.3 mL/kg.

Techniques:

Journal: Molecules

Article Title: Pharmacological Effects of “Jutsu” ( Atractylodis rhizome and Atractylodis lanceae rhizome ) on 1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-Induced Head Twitch Response in Mice (I)

doi: 10.3390/molecules190914979

Figure Lengend Snippet: Effect of atractylenolide III and β-eudesmol on DOI-induced HTR in mice. Each column represents the mean ± S.E. of 9 mice. * p < 0.05, ** p < 0.01 vs. Control (one-way ANOVA followed by Dunnett’s test).

Article Snippet: Atractylenolide III (Lot No. WEN2356) and β-eudesmol (Lot No.WEG2032) were purchased from Wako Pure Chemical Industries Ltd. (Tokyo, Japan) and were dissolved in corn oil (Lot No.2012H2137, Junsei Chemical Co., Ltd., Tokyo, Japan), while control animals were orally administered with corn oil at a volume of 3.3 mL/kg.

Techniques:

Journal: Molecules

Article Title: Pharmacological Effects of “Jutsu” ( Atractylodis rhizome and Atractylodis lanceae rhizome ) on 1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-Induced Head Twitch Response in Mice (I)

doi: 10.3390/molecules190914979

Figure Lengend Snippet: Postulated active site in the chemical structure in atractylenolide III compared to serotonin (5-HT).

Article Snippet: Atractylenolide III (Lot No. WEN2356) and β-eudesmol (Lot No.WEG2032) were purchased from Wako Pure Chemical Industries Ltd. (Tokyo, Japan) and were dissolved in corn oil (Lot No.2012H2137, Junsei Chemical Co., Ltd., Tokyo, Japan), while control animals were orally administered with corn oil at a volume of 3.3 mL/kg.

Techniques:

Journal: Biomolecules & Therapeutics

Article Title: Unraveling Stereochemical Structure-Activity Relationships of Sesquiterpene Lactones for Inhibitory Effects on STAT3 Activation

doi: 10.4062/biomolther.2023.210

Figure Lengend Snippet: Conformational analysis of sesquiterpene lactones. (A) 2D chemical structures of alantolactone and atractylenolide I. (B) Geometry optimized 3D structures of alantolactone (green) and atractylenolide I (cyan) were aligned based on their lactone rings. (C) Schematic diagram for determining the torsion angle between sesquiterpene skeleton-lactone ring (S-L torsion angle). We calculated Van der Waals (VdW) strains in SH2 binding pocket for alantolactone (D) and atractylenolide I (E). Putative VdW strains were visualized as red flat cylinders. (F) Geometry optimized 3D structures of sesquiterpene lactones were aligned based on their lactone rings. Sesquiterpene lactones, namely alantolactone, isoalantolactone, and parthenolide, which demonstrated over 50% inhibitory effects on STAT3 activation, are shown in green. (G) Correlation between S-L torsion angles and relative p-STAT3 at 10 μM of nine sesquiterpene lactones.

Article Snippet: Alantolactone, isoalantolactone, costunolide, dehydrocostus lactone, parthenolide, atractylenolide I, atractylenolide II, atractylenolide III, and sclareolide, were purchased from Tauto Biotech (Shanghai, China).

Techniques: Binding Assay, Activation Assay